3rd Frankfurt Conference on
The international Frankfurt Conference on Quality Control brings scientists on all career stages together to discuss mechanisms of cellular homeostasis and their impact on pathogenesis of major human diseases.
Cellular quality control mechanisms are essential to maintain cell survival and homeostasis, and their malfunction leads to severe damage, ultimately contributing to and/or causing a variety of malignant and fatal diseases. Whilst many molecular mechanisms driving pathogenesis have been uncovered, we are only beginning to understand the interconnectivity and concerted regulation of these pathways and the influence of contextual factors. A deeper knowledge of the role of cellular quality control pathways, e.g. in cancer, neurodegeneration, inflammatory and infectious diseases holds enormous potential to better understand disease onset and/or progression and potentially develop novel treatments.
Following the first meeting in 2016 which focused on ubiquitination and autophagy machineries that facilitate degradative quality control of proteins and organelles and a second meeting in 2018 centered around signaling networks and quality control in development, this year’s third Frankfurt Conference on Quality Control features interdisciplinary sessions that cover topics including Immunity and Quality Control, Regulatory Events and the Interplay between Autophagy, Ubiquitin and Proteostasis.